Ethinylestradiol/desogestrel

Ethinylestradiol/desogestrel (EE/DSG), sold under the brand name Marvelon among others, is a fixed-dose combination of ethinylestradiol (EE), an estrogen, and desogestrel (DSG), a progestin, which is used as a birth control pill to prevent pregnancy in women.[2][3][5][6] It is taken by mouth.[3]

Desogestrel/ethinylestradiol
Ethinylestradiol
Desogestrel
Combination of
EthinylestradiolEstrogen
DesogestrelProgestogen (Progestin)
Clinical data
Trade namesMarvelon, Desogen, Ortho-cept, others
Other namesEE/DSG, EE-DSG, DSG+EE
AHFS/Drugs.comProfessional Drug Facts
MedlinePlusa601050
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number

It was approved for medical use in the United Kingdom in 1981,[2] and in the United States in 1992.[3] In 2021, it was the 137th most commonly prescribed medication in the United States, with more than 4 million prescriptions.[7][8]

See also

References
  1. "Product monograph brand safety updates". Health Canada. 7 July 2016. Retrieved 3 April 2024.
  2. "Marvelon Tablets - Summary of Product Characteristics (SmPC)". (emc). 11 March 2021. Retrieved 18 June 2021.
  3. "Desogen Tablets (desogestrel and ethinyl estradiol tablets USP)". DailyMed. 18 June 2018. Retrieved 18 June 2021.
  4. "List of nationally authorised medicinal products" (PDF). European Medicines Agency.
  5. Pundir J, Coomarasamy A (21 April 2016). Gynaecology: Evidence-Based Algorithms. Cambridge University Press. pp. 260–. ISBN 978-1-316-30110-4.
  6. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans; World Health Organization; International Agency for Research on Cancer (2007). Combined Estrogen-progestogen Contraceptives and Combined Estrogen-progestogen Menopausal Therapy. World Health Organization. pp. 435, 436, 455, 459. ISBN 978-92-832-1291-1.
  7. "The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
  8. "Desogestrel; Ethinyl Estradiol - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.


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