EIF3CL

Eukaryotic translation initiation factor 3 subunit C like is a protein that in humans is encoded by the EIF3CL gene. [5]

EIF3CL
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEIF3CL, eukaryotic translation initiation factor 3 subunit C like
External IDsMGI: 1926966; GeneCards: EIF3CL; OMA:EIF3CL - orthologs
Orthologs
SpeciesHumanMouse
Entrez

728689

56347

Ensembl

ENSG00000205609

ENSMUSG00000030738

UniProt

B5ME19

Q8R1B4

RefSeq (mRNA)

NM_001099661
NM_001317856
NM_001317857

NM_146200

RefSeq (protein)

NP_001093131
NP_001304785
NP_001304786

NP_666312

Location (UCSC)Chr 16: 28.38 – 28.4 MbChr 7: 126.15 – 126.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

The protein encoded by this gene is a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex. The encoded protein is nearly identical to another protein, eIF3c, from a related gene. The eIF3 complex binds the 40S ribosome and mRNAs to enable translation initiation. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015].

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000205609 Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000030738 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Eukaryotic translation initiation factor 3 subunit C like". Retrieved 2020-04-15.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.