PMDTT

PMDTT is an antiviral phosphonate nucleoside.[1]

PMDTT
Names
IUPAC name
({[(3R,5R)-5-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)oxolan-3-yl]oxy}methyl)phosphonic acid
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C10H15N2O7P/c1-6-3-12(10(14)11-9(6)13)8-2-7(4-18-8)19-5-20(15,16)17/h3,7-8H,2,4-5H2,1H3,(H,11,13,14)(H2,15,16,17)/t7-,8-/m1/s1
    Key: ICGMUOZWOCLUNS-HTQZYQBOSA-N
  • InChI=1/C10H15N2O7P/c1-6-3-12(10(14)11-9(6)13)8-2-7(4-18-8)19-5-20(15,16)17/h3,7-8H,2,4-5H2,1H3,(H,11,13,14)(H2,15,16,17)/t7-,8-/m1/s1
    Key: ICGMUOZWOCLUNS-HTQZYQBOBH
  • CC1=CN(C(=O)NC1=O)[C@H]2C[C@H](CO2)OCP(=O)(O)O
Properties
C10H15N2O7P
Molar mass 306.211 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. Wu, Tongfei; Froeyen, Matheus; Kempeneers, Veerle; Pannecouque, Christophe; Wang, Jing; Busson, Roger; De Clercq, Erik; Herdewijn, Piet (13 April 2005). "Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents". Journal of the American Chemical Society. 127 (14): 5056–5065. doi:10.1021/ja043045z. ISSN 0002-7863. PMID 15810840.
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