Urolithin B

Urolithin B (UB)[1] is an urolithin, a type of phenolic compounds produced in the human gut after absorption of ellagitannins-containing food such as pomegranate,[2] strawberries, red raspberries, walnuts or oak-aged red wine.[3] Urolithin B is found in the urine in the form of urolithin B glucuronide.

Urolithin B
Names
Preferred IUPAC name
3-Hydroxy-6H-dibenzo[b,d]pyran-6-one
Other names
Uro-B
3-Hydroxyurolithin
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.236.446
KEGG
UNII
  • InChI=1S/C13H8O3/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)16-12(10)7-8/h1-7,14H
    Key: WXUQMTRHPNOXBV-UHFFFAOYSA-N
  • C1=CC=C2C(=C1)C3=C(C=C(C=C3)O)OC2=O
Properties
C13H8O3
Molar mass 212.204 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

References
  1. Ghosh N, Das A, Biswas N, Gnyawali S, Singh K, Gorain M, Polcyn C, Khanna S, Roy S, Sen CK (19 November 2020). "Urolithin A augments angiogenic pathways in skeletal muscle by bolstering NAD+ and SIRT1". Nature.com. 10 (1). Scientific Reports: 20184. doi:10.1038/s41598-020-76564-7. PMC 7678835. PMID 33214614.
  2. Bialonska D, Kasimsetty SG, Khan SI, Ferreira D (11 November 2009). "Urolithins, intestinal microbial metabolites of Pomegranate ellagitannins, exhibit potent antioxidant activity in a cell-based assay". J Agric Food Chem. 57 (21): 10181–6. doi:10.1021/jf9025794. PMID 19824638.
  3. Cerdá B, Tomás-Barberán FA, Espín JC (2005). "Metabolism of Antioxidant and Chemopreventive Ellagitannins from Strawberries, Raspberries, Walnuts, and Oak-Aged Wine in Humans: Identification of Biomarkers and Individual Variability". Journal of Agricultural and Food Chemistry. 53 (2): 227–235. doi:10.1021/jf049144d. PMID 15656654.


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