IN EARLY 2020, with the coronavirus pandemic tearing across the world, most people thought it unlikely that a vaccine would arrive any time soon. And as work to develop vaccines began, there were dire warnings of the difficulties ahead. That is why it is so remarkable that, heading into 2021, it seems likely that one or more working vaccines will soon be available. That this can be said with such certainty reflects the number and diversity of approaches being taken.
What is the role of "That" in the beginning of the last sentence? Under what circumstances a sentence can start with "That"?
X, for someX, means that the speaker is vouching for the truth ofX. That's not true for a simple that, which is a Complementizer, a kind of word that doesn't have any meaning but just marks a particular kind of construction, like the complementizer to marks infinitives. The complementizer that marks tensed complement clauses, object complements like I think that I shall never see..., and subject complements like That I left annoyed her, aka It annoyed her that I left. – John Lawler Dec 08 '20 at 00:19