I have heard two pronunciations for the word tissue. Tishoo and Tisyou.
Tishoo is of course the one in common use but what is the current status on Tisyou ?
It ''feels'' like an archaic way of pronouncing tissue but that might not be true.
It also ''feels'' more British and more formal.
I found myself using Tishoo for paper and Tisyou for organic tissue. As in skin tissue.
What is the status/useage of the tisyou pronunciation ?